The DG wouldn't be a really great design even if you had the technology to build it. Since it's a winged vessel, its best use would be as a surface to orbit shuttle on Earth, or any other planet with a substantial atmosphere. For any Earth-moon or interplanetary flight the wings are just dead weight, so such a mission would be left to purpose built craft without wings, streamlining, or landing gear. But the main engines are too overpowered and have too much fuel for surface-to-orbit operations (weight penalty), and the scrams probably aren't good enough to be worthwhile. The hovers are also impractical.
What you'd really want for such a craft would be this:
The main engines are obviously something nuclear, probably fusion, given the ISP of 40 km/s. If you can use that to provide the heat for the scrams, rather than the chemfuel they seem to use, then they don't actually need fuel beyond what's needed to power your fusion reactor (which comes out, I think, to a few grams/sec). Also, if you can build a fusion reactor/drive/scramjet, it's fairly likely that you can deal with temperatures high enough to operate the scrams up to a good fraction of orbital velocity. Once you get going the fastest you can with your scrams you can cut in the mains, which probably don't need a full 40 km/s of ISP, and certainly don't need the full thrust they have (they might be able to get by with a tenth or so of that). Another thing is that you wouldn't want to use the mains to accelerate you up to your scram ignition speed: you'd probably want some type of turbine or other low-speed engine, which could, like the scrams, be fusion heated rather than using chemfuel. Since the mains are now powering much less of the ascent, and since we aren't designing the thing to go beyond Earth orbit (geosynch is probably the highest we'll go), we can cut out a huge portion of the propellant reserve, freeing up space and weight for cargo.