a human from Earth, Mars or Venus would not be able to live long-term in freefall, and genetically engineered jellypeople would not be able to survive on any of those planets.
I may not be genetically engineered (if so I'm not aware of it), but as a 'jelly-person' I am indeed surviving on planet earth
Although I was only thinking about skeleton-decay in terms of present-day flights/long term missions to the moon and Mars, or even more distant planets in this solar-system, the longer-term issues of human survival are also very interesting.
Maybe we will eventually become like octopuss' with brains?

Then we could live on earth and maybe on the moon europa, and probably in zero-G also.
Anyway, I read that 438 days is the current record for longest stay in micro-gravity by a current living human that was able to transition back to healthy life in 1G.
However, a base on either the moon or on Mars would probably require a human to spend several years in a below-1G environment (1000+ days probably), and this might still have some kind of lasting unwanted influence on human physiology (thinking that maybe there is some 'break-even' period for how long it is possible to live in zero-G before it becomes dangerous to return to a 1G environment again)
If people degrade past such a 'break-even' point, by a 2-3 year mission to Mars, then returning them to earth could be a real problem. Maybe even impossible.
A base on the moon might be less of a problem, if crew-shifting could take place every year of half-year (atleast the 438 day record would imply so)
Ofcourse if it is just the length of a flight, to either the moon or Mars, then there is no huge problem since a centrifuge, or maybe some kind of swing or other gravity-making contraption, could probably be built on the planet much more easily than off a planet.
Something like this maybe: