If all engines have the same ISP, then that is the overall ISP. If they have different ISPs, then calculating the DV becomes a nightmare.
Not really. You only need to know what ISP means.
ISP is the impulse you get per kg propellant consumed by your engine. And impulse is in its simplest definition force multiplied by time. Which means you can also interpret it as :
Thrust force by fuel consumption.
[math]I_{sp} = \frac{F \times t}{m}[/math]
So, for your whole rocket stage, it is just the force you get by the fuel that you burn.
Now I that example, ISP was tripled by force was divided by three. This means, that the mass flow or fuel consumption was changed a lot:
[math]\frac{m}{t} = \frac{F}{I_sp} [/math]
and was changed relative by:
[math]\frac{\frac{1}{3}}{3} = \frac{1}{3 \times 3} = \frac{1}{9}[/math]
So, in the same time, your spacecraft now consumes 1/9th of the fuel.
Now, for the maneuvers in space, only specific impulse matters, by rocket equation:
[math]\Delta v = I_{sp} \times \log \left ( \frac{m_0}{m_b} \right )[/math]
Since you did not change the propellant mass but only tripled your ISP, your spacecraft has now three times the DV. As long as gravitation does not have much effect in your maneuvers, the longer burn time has no negative effect at all.