I haven't tried it myself, but the AutoFCS reentry guidance will probably work. The deorbit burn and RCS attitude control will have to be done manually.
As a worst case scenario, I think you could turn off the AFCS autopilot and fly the shuttle manually, using the HUD flight director drawn by AutoFCS.
As a worst case scenario, I think you could turn off the AFCS autopilot and fly the shuttle manually, using the HUD flight director drawn by AutoFCS.