I was impressed during the very first seconds. Then I realized that the pieces do not rotate, which is not much realistically after such an obvious damage/collision/explosion. But the damages look almost real. Well done.
As for the music: James Honors Apollo 13 soundtracks are nice but something like well-worn after 14 years. I'd like to recommend Philip Sheppards In the Shadow of the Moon- soundtracks to those who intend to make space flight videos. But honestly, both, James Honor and Philip Sheppard Apollo soundtracks, actually only fit to Apollo. At least to my taste, because they're made for Apollo and I always relate them to Apollo whenever I hear them. But newly, I can not wait to get the soundtracks of When we left Earth.
Anyway, such a scenario shown in this nicely made video is more than unlikely. Such a fatal loss never happened in orbit within 48 years of human space flight history. The most likely scenario for each upcoming Shuttle mission is a damge, similar to that of Columbia in 2003 caused by foam loss during early ascent, so fatal in size and location that it could make a repair and re-entry impossible.
But however, like Chris Kraft (among other things director of Flight Operations - Apollo) tends to say: "We know nothing is certain. And particular in space flight is anything certain"...